Inventor
1. WO WO/2011/101245 -NITRIC OXIDE RELEASING COMPOUNDS FOR THE TREATMENT OF NEUROPATHIC PAIN 25.08.2011 C07C 203/04 PCT/EP2011/051484 NICOX S.A. ALMIRANTE, Nicoletta
The invention relates to nitrooxyderivatives of Gamma- aminobutyric acid analogs (GABA analogs) for treating neuropathic pain and in particular diabetic neuropathy. The invention also relates to pharmaceutical formulation comprising such derivatives, to a process for their preparation.
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Pub. No.: WO/2011/101245 International Application No.: PCT/EP2011/051484
Publication Date: 25.08.2011 International Filing Date: 02.02.2011
IPC: C07C 203/04 (2006.01), C07C 271/16 (2006.01), C07D 317/40 (2006.01)
Applicants: NICOX S.A. [FR/FR]; Taissounières HB4 - 1681 route des Dolines - BP313 F-06560 Sophia Antipolis -Valbonne (FR) (For All Designated States Except US).
ALMIRANTE, Nicoletta [IT/IT]; (IT) (For US Only).
IMPAGNATIELLO, Francesco [IT/IT]; (IT) (For US Only).
NICOTRA, Alessia [IT/IT]; (IT) (For US Only).
MANDELLI, Valentino [IT/IT]; (IT) (For US Only).
BRAMBILLA, stefania; (IT) (For US Only)
Inventors: ALMIRANTE, Nicoletta; (IT).
IMPAGNATIELLO, Francesco; (IT).
NICOTRA, Alessia; (IT).
MANDELLI, Valentino; (IT).
BRAMBILLA, stefania; (IT)
Agent: BARCHIELLI, Giovanna; Via L. Ariosto 21 I-20091 Bresso (Milano) (IT)
Priority Data:
61/305,664 18.02.2010 US
10193138.4 30.11.2010 EP
Title (EN) NITRIC OXIDE RELEASING COMPOUNDS FOR THE TREATMENT OF NEUROPATHIC PAIN
(FR) COMPOSÉS LIBÉRANT DU MONOXYDE D'AZOTE POUR LE TRAITEMENT DE LA DOULEUR NEUROPATHIQUE
Abstract: front page image
(EN) The invention relates to nitrooxyderivatives of Gamma- aminobutyric acid analogs (GABA analogs) for treating neuropathic pain and in particular diabetic neuropathy. The invention also relates to pharmaceutical formulation comprising such derivatives, to a process for their preparation.
(FR) L'invention concerne des dérivés nitrooxy d'analogues de l'acide Gamma-aminobutyrique (analogues de GABA) pour le traitement de la douleur neuropathique et, en particulier, de la neuropathie diabétique. L'invention concerne également une formulation pharmaceutique comprenant de tels dérivés et un procédé pour leur préparation.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)